Alkaloids and Phenolics of Colchicum cilicicum1,2

N. Sütlüpinar; A. Husek; H. Potěšilová; S. Dvořáčková; V. Hanuš; P. Sedmera; V. Šimánek

doi:10.1055/s-2006-962417

Planta Medica, Table of Contents

Planta Med 1988; 54(3): 243-245
DOI: 10.1055/s-2006-962417

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Alkaloids and Phenolics of Colchicum cilicicum ^1,2

N. Sütlüpinar³ , A. Husek⁴ , H. Potěšilová⁴ , S. Dvořáčková⁴ , V. Hanuš⁵ , P. Sedmera⁶ , V. Šimánek⁴

³Department of Pharmacognosy, University of Istanbul, Istanbul, Turkey.
⁴Institute of Medical Chemistry, Palacký University, 775 15 Olomouc, Czechoslovakia.
⁵The J. Heyrovský Institute of Physical Chemistry and Electrochemistry, Czechoslovak Academy of Sciences, Prague, Czechoslovakia.
⁶Institute of Microbiology, Czechoslovak Academy of Sciences, Prague, Czechoslovakia.

1 Part CI in the series: Substances from the Plant of the Subfamily Wurmbaeoideae and their Derivatives; Part C: Phytochemistry 26, 1031 (1987).2 Dedicated to Professor Jiří Slavík, Brno. on the occasion of his 65th birthday.

Abstract

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Abstract

The distributions of the alkaloids colchicine, 2-demethylcolchicine, 3-demethylcolchicine, demecolcine, 2-demethyldemecolcine, and 3-demethyldemecolcine in the corms, stems, leaves, flowers, and seeds of Colchicum cilicicum were analysed by HPLC. In addition, the alkaloids cornigerine, N-formyl-N-deacetylcolchicine, N-methyl-demecolcine, β-lumicolchicine, γ-lumicolchicine, β-lumidemecolcine, γ-lumidemecolcine, and N-ethoxycarbonyldemecolcine were identified, the last named being reported for the first time from a Colchicum species. The flavones luteolin and apigenin were isolated and benzoic, 2-hydroxy-6-methoxybenzoic, and vanillic acids were also detected.

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Alkaloids and Phenolics of Colchicum cilicicum 1,2

Alkaloids and Phenolics of Colchicum cilicicum ^1,2