Planta Med 1989; 55(6): 540-543
DOI: 10.1055/s-2006-962089
Papers

© Georg Thieme Verlag Stuttgart · New York

A New Approach to the Production of Chamomile Extracts

R. Carle1 , B. Dölle2 , E. Reinhard3
  • 1Pharma-Forschung der ASTA Pharma AG, Weismüllerstraße 45, D-6000 Frankfurt am Main, Federal Republic of Germany
  • 2Qualitätskontrolle der ASTA Pharma AG, Weismüllerstraße 45, D-6000 Frankfurt am Main, Federal Republic of Germany
  • 3Lehrstuhl für Pharmazeutische Biologie der Universität Tübingen, Auf der Morgenstelle 8, D-7400 Tübingen, Federal Republic of Germany
Further Information

Publication History

1989

Publication Date:
24 January 2007 (online)

Abstract

Extracts from fresh flower heads of Chamomilla recutita were prepared for the first time. The stability of those extracts was compared in tests to that of extracts from dried plant material with regard to lipophilic and hydrophilic compounds. Whereas extracts based on dried flower heads showed a considerable decrease in matricine content within 10 months, extracts of fresh plant material were stable in every respect. Frozen flower heads could be stored without any loss of volatile substances. Even matricine and the spiro-ethers proved to be stable. In contrast, dried chamomile flowers lost about 70% of their matricine content within two years even when stored under controlled conditions. Furthermore, freezing the chamomile flowers resulted in higher yields of essential oil and its compounds than any of the various drying procedures tested.

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