Two New Glucosides from Hypoxis obtusa: Obtuside A and Obtuside B1,5

C. Galeffi; G. Multari; Y. De Vicente; I. Messana; M. Nicoletti; G. B. Marini-Bettolo

doi:10.1055/s-2006-962019

Planta Medica, Table of Contents

Planta Med 1989; 55(3): 318-320
DOI: 10.1055/s-2006-962019

Papers

Two New Glucosides from Hypoxis obtusa: Obtuside A and Obtuside B^1,5

C. Galeffi² , G. Multari² , Y. De Vicente² , I. Messana⁴ , M. Nicoletti³ , G. B. Marini-Bettolo³ ^, ⁴

²Laboratorio di Chimica del Farmaco, Istituto Superiore di Sanità, V. le R. Elena 299, I-00161 Roma, Italy
³Dipartimento di Biologia Vegetale, Università La Sapienza, Roma, Italy
⁴Istituto di Chimica e Centro CNR per lo Studio dei Recettori e delle Molecole biologicamente Attive, Università Cattolica del S. Cuore, Roma, Italy

1 Part XIV in the series: Research on African Medicinal Plants; Part XIII: Galeffi, C., Multari, G., Msonthi, J. D., Nicoletti, M., Marini-Bettolo, G. B. (1987) Tetrahedron 43, 35195 Dedicated to the memory of Prof. Edgar Lederer

Abstract

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Abstract

From the rhizomes of Hypoxis obtusa two monoglucosides having the same aglycone as hypoxoside, 1-(3′,4′- dihydroxyphenyl)-5-(3″,4″-dihydroxyphenyl)-1-pen-ten-4-yne, have been obtained. By methylation followed by hydrogenation they have been transformed into the same compound, 1-(3′-methoxy-4′-O-β-D-glucopyranosyl-phenyl)-5-(3″-4″-dimethoxyphenyl)-pentane, likewise obtainable through partial hydrolysis of hypoxoside.

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