Planta Med 1992; 58(6): 493-495
DOI: 10.1055/s-2006-961533
Papers

© Georg Thieme Verlag Stuttgart · New York

Structure and Hepatoprotective Activity of a Biflavonoid from Canarium manii

K. K. Anand1 , V. N. Gupta1 , V. Rangari2 , Bhupinder Singh1 , B. K. Chandan1
  • 1Department of Pharmacology, Regional Research Laboratory, Canal Road, Jammu-Tawi 180 001, India
  • 2College of Pharmacy, Nasik 422 001, India
Further Information

Publication History

1991

Publication Date:
05 January 2007 (online)

Abstract

Canarium manii (Burseraceae) was chemically investigated and the presence of the biflavonoid agathisflavone is reported for the first time from this plant. Pharmacologically, this biflavonoid in doses 50.0 mg and 100.0 mg given orally exhibited dose-dependent hepatoprotective activity against experimentally-induced carbon tetrachloride-hepatotoxicity in rats and mice.