Planta Med 1992; 58(6): 493-495
DOI: 10.1055/s-2006-961533

© Georg Thieme Verlag Stuttgart · New York

Structure and Hepatoprotective Activity of a Biflavonoid from Canarium manii

K. K. Anand1 , V. N. Gupta1 , V. Rangari2 , Bhupinder Singh1 , B. K. Chandan1
  • 1Department of Pharmacology, Regional Research Laboratory, Canal Road, Jammu-Tawi 180 001, India
  • 2College of Pharmacy, Nasik 422 001, India
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Publication History


Publication Date:
05 January 2007 (online)


Canarium manii (Burseraceae) was chemically investigated and the presence of the biflavonoid agathisflavone is reported for the first time from this plant. Pharmacologically, this biflavonoid in doses 50.0 mg and 100.0 mg given orally exhibited dose-dependent hepatoprotective activity against experimentally-induced carbon tetrachloride-hepatotoxicity in rats and mice.