© Georg Thieme Verlag Stuttgart · New York
Structure and Hepatoprotective Activity of a Biflavonoid from Canarium manii
05 January 2007 (online)
Canarium manii (Burseraceae) was chemically investigated and the presence of the biflavonoid agathisflavone is reported for the first time from this plant. Pharmacologically, this biflavonoid in doses 50.0 mg and 100.0 mg given orally exhibited dose-dependent hepatoprotective activity against experimentally-induced carbon tetrachloride-hepatotoxicity in rats and mice.
Canarium manii - nutshell - biflavonoid - hepatoprotective activity - CCl4-induced hepatotoxicity