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Planta Med 1992; 58(4): 365-367
DOI: 10.1055/s-2006-961486
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© Georg Thieme Verlag Stuttgart · New York

New Eremophilane Type Lactones from the Roots of Ligularia veitchiana

Zhongjian Jia, Yu Zhao, Renxiang Tan
  • State Key Laboratory of Applied Organic Chemistry at Lanzhou University. Lanzhou 730000, People's Republic of China
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Publication History

1991

Publication Date:
05 January 2007 (online)

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Abstract

Phytochemical investigation of the roots of Ligularia veitchiana has resulted in the characterization of two new eremophilanolides together with β-sitosterol, stigmasterol, taraxol, and liguhodgsonal whose structure was further confirmed by the 13C-NMR techniques. The structures of the new constituents were elucidated by spectroscopic methods and shown to be 1β, 10β-epoxy-6β(2′-hydroxymethylacryloyloxy)-8β-hydroxy-eremophila-7(11)-en-12,8α-olide (1) and 1β, 10β-epoxy-6β-(2′-hydroxymethylacryloyloxy)-8β-ethoxy-eremophila-7(11)-en-12,8α-olide (2).

Key words

Ligularia veitchiana - Compositae - sesquiterpenes - sesquiterpene lactones - eremophilanolides

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