Planta Med 1992; 58(3): 234-236
DOI: 10.1055/s-2006-961442

© Georg Thieme Verlag Stuttgart · New York

Effect of Galphimia glauca Methanolic Extract on Neuropharmacological Tests

J. Tortoriello, X. Lozoya
  • Traditional Medicine and Drug Development Research Unit, Mexican Institute of Social Security, IMSS, Xochitepec, CP 6790,México
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Publication History


Publication Date:
05 January 2007 (online)


Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine for the treatment of nervous excitment. A methanolic extract from its aerial parts (MEGA) was tested in several neuropharmacological animal models including among others: hypothermic activity, barbiturate potentation, protection against strychnine- and leptazol-induced convulsions. The combined data obtained from all biological models demonstrate the sedative property of this plant product.