Isolierung und Struktur weiterer neuer Saponine aus Solidago canadensis

Abstract

Four new main saponins (canadensis-saponins 5-8) (compounds 5-8) were isolated from Solidago canadensis L. (Asteraceae). Using GC/MS, FAB-MS, and mainly 2D-NMR techniques their structures were identified as 3-O-[β-D-glucopyranosyl(1→3)-β-D-glucopyranosyl]-28-O-{β-D-galactopyranosyl(1→2)-α-L-rhamnopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-[β-D-xylopyranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-[β-D-apio-D-furanosyl-(1→3)]-β-D-6-deoxyglucopyranosyl-(1→)}-bayogenin(5),3-O-[β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl]-28-O-{β-D-galactopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-[β-D-xylopyranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-[β-D-apio-D-furanosyl-(1→3)]-arabinopyranosyl-(1→)}bayogenin(6),3-O-[β-D-glucopyranosyl-(1→3)-(β-D-glucopyranosyl]-28-O- {β-D-galactopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-[β-D-xylopyranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-β-D-6-deoxyglucopyranosyl-(1→)}-bayogenin (7), and 3-O-[β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl]-28-{O-β-D-galactopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-[β-D-xylopyranosyl-(1→3)]-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]arabinopyranosyl-(&1rarr;){-bayogenin(8).

Solidago canadensis - Asteraceae - triterpene saponin - bayogenin-glycosides