On the Influence of the Sugar Moiety on the Antigonadotropic Activity of Luteoline Glycosides

H. G. Gumbinger; H. Winterhoff; R. Wylde; A. Sosa

doi:10.1055/s-2006-961388

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Planta Med 1992; 58(1): 49-50
DOI: 10.1055/s-2006-961388

Paper

On the Influence of the Sugar Moiety on the Antigonadotropic Activity of Luteoline Glycosides

H. G. Gumbinger² , H. Winterhoff² , R. Wylde¹ , A. Sosa¹

¹Centre C.N.R.S.I.N.S.E.R.M. de Pharmakologie Endocrinologie, B.P. 5055, F-34033 Montpellier Cedex, France
²Institut für Pharmakologie und Toxikologie der Universität, Domagkstr. 12, D(W)-4400 Münster, Federal Republic of Germany

Further Information

Publication History

1991

Publication Date:
04 January 2007 (online)

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Abstract

Luteolin-7-glucoside and luteolin-7-glucuronide were isolated from Lycopus europaeus L. (Lamiaceae) and identified by ¹H- and ¹³C-NMR spectroscopy. Luteolin-7-glucuronide proved to be active against PMSG in vitro as well as in vivo, whereas the other flavone glycosides occurring in the plant were completely inactive.

Key words

Lycopus europaeus - Lamiaceae luteolin-7-glucoside - luteolin-7-glucuronide - antigonadotropic activity - PMSG

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