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Planta Med 1990; 56(4): 374-376
DOI: 10.1055/s-2006-960986
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© Georg Thieme Verlag Stuttgart · New York

Molluscicidal and Antischistosomal Activities of Zingiber officinale

Clement O. Adewunmi1 , Babajide O. Oguntimein1 , Peter Furu2
  • 1Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
  • 2Danish Bilharziasis Laboratory, Jaegersborg Allé 1D, DK-2920 Charlottenlund, Denmark
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Publikationsverlauf

1989

Publikationsdatum:
05. Januar 2007 (online)

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Abstract

Experiments were conducted to study the major constituents of Zingiber officinale responsible for its molluscicidal activity and the effect of the active component on different stages of Schistosoma mansoni. Gingerol and shogaol exhibited potent molluscicidal activity on Biomphalaria glabrata. Gingerol (5.0 ppm) completely abolished the infectivity of Schistosoma mansoni miracidia and cercariae in B. glabrata and mice, respectively, indicating that the molluscicide is capable of interrupting schistosome transmission at a concentration lower than its molluscicidal concentrations.

Key words

Molluscicide - Zingiber officinale - Schistosoma mansoni - Biomphalaria glabrata