Molluscicidal and Antischistosomal Activities of Zingiber officinale

Clement O. Adewunmi; Babajide O. Oguntimein; Peter Furu

doi:10.1055/s-2006-960986

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Planta Med 1990; 56(4): 374-376
DOI: 10.1055/s-2006-960986

Papers

Molluscicidal and Antischistosomal Activities of Zingiber officinale

Clement O. Adewunmi¹ , Babajide O. Oguntimein¹ , Peter Furu²

¹Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
²Danish Bilharziasis Laboratory, Jaegersborg Allé 1D, DK-2920 Charlottenlund, Denmark

Further Information

Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

Experiments were conducted to study the major constituents of Zingiber officinale responsible for its molluscicidal activity and the effect of the active component on different stages of Schistosoma mansoni. Gingerol and shogaol exhibited potent molluscicidal activity on Biomphalaria glabrata. Gingerol (5.0 ppm) completely abolished the infectivity of Schistosoma mansoni miracidia and cercariae in B. glabrata and mice, respectively, indicating that the molluscicide is capable of interrupting schistosome transmission at a concentration lower than its molluscicidal concentrations.

Key words

Molluscicide - Zingiber officinale - Schistosoma mansoni - Biomphalaria glabrata

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