New Polyindolenine Alkaloids from Calycodendron milnei

Y. Adjibadé; H. Saad; T. Sévenet; B. Kuballa; J. C. Quirion; R. Anton

doi:10.1055/s-2006-960927

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Planta Med 1990; 56(2): 212-215
DOI: 10.1055/s-2006-960927

Papers

New Polyindolenine Alkaloids from Calycodendron milnei

Y. Adjibadé¹ , H. Saad¹ , T. Sévenet² , B. Kuballa¹ , J. C. Quirion² , R. Anton¹

¹Université Louis Pasteur, Faculté de Pharmacie, Laboratoire de Pharmacognosie, B.P. 24, F-67401 Illkirch Cédex, France
²Institut de Chimie des Substances Naturelles, C.N.R.S., F-91198 Gif-sur-Yvette, France

Further Information

Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

Four new alkaloids, representing the first members of new groups of polyindolinic alkaloids, have been isolated from the aerial parts of Calycodendron milnei along with other alkaloids. The names vatine, its stereoisomer vatine A, vatamine, and vatamidine are proposed. They are polymers of six, seven, and eight N _b-methyltryptamine units, respectively.

Key words

Calycodendron milnei - Rubiaceae - alkaloid - polyindolenines - vatine - vatamine - vatamidine - N _b-methyltryptamines - structure elucidation