© Georg Thieme Verlag Stuttgart · New York
A Novel N 6-Substituted Adenosine Isolated from Mi Huan Jun (Armillaria mellea) as a Cerebral-Protecting Compound
05 January 2007 (online)
Successive purification of a crude extract of cultured Mi Huan Jun mycelia, followed by an assay of the effect on complete ischemia in mice, led to the isolation of a new compound with cerebral protecting activity, hereafter designated as AMG-1. The structure of AMG-1 was proposed as being 6-(5-hydroxy-2-pyridylmethylamino)-9-β-ribofuranosylpurine (1) on the basis of its UV, mass, 1H-NMR, and 13C-NMR spectra.
Armillaria mellea - cytokinin - N 6-substituted adenosine - cerebral-protecting compound