Abstract
Successive purification of a crude extract of cultured Mi Huan Jun mycelia, followed
by an assay of the effect on complete ischemia in mice, led to the isolation of a
new compound with cerebral protecting activity, hereafter designated as AMG-1. The
structure of AMG-1 was proposed as being 6-(5-hydroxy-2-pyridylmethylamino)-9-β-ribofuranosylpurine
(1) on the basis of its UV, mass, 1H-NMR, and 13C-NMR spectra.
Key words
Armillaria mellea
- cytokinin -
N
6-substituted adenosine - cerebral-protecting compound
