Planta Medica, Inhaltsverzeichnis Planta Med 1990; 56(1): 24-26DOI: 10.1055/s-2006-960876 Paper © Georg Thieme Verlag Stuttgart · New York Pharmacological Effects of Three Phenylpropanoid Glycosides from Mussatia Ernesto Cano1 , Manuel Veiga2 , Carlos Jiménez3 , Ricardo Riguera3 1Departamento de Farmacología, Farmaciay Tecnología Farmacéutica, Facultad de Farmacia, Santiago de Compostela, Spain 2Departamento de Microbiología y Parasitología, Facultad de Farmacia, Santiago de Compostela, Spain 3Departamento de Química Orgánica, Santiago de Compostela, Spain Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract The phenylpropanoid glycosides 1 (4-cinnamoylmussatioside), 2 (4-dimethylcaffeoylmussatioside), and 3 (4-p-methoxycinnamoylmussatioside) isolated from the methanolic extract of Mussatia sp. showed inhibitory action on ADP-induced rat platelet aggregation. The order of activity was 1 > 2 > 3. This antiplatelet effect is likely to be related to the reported inhibition of cAMP-phosphodiesterase. On the other hand, compounds 1-3 had no effect on blood pressure and heart rate, on microbial growth, or on prostaglandin biosynthesis. Key words Mussatia - phenylpropanoid glycosides - mussatiosides - pharmacological activity PDF (268 kb)
