Isolation and Identification of a New Antifungal Sesquiterpene Lactone from Inula viscosa

Michal Maoz; Yoel Kashman; Ishak Neeman

doi:10.1055/s-2006-960780

Planta Medica, Inhaltsverzeichnis

Planta Med 1999; 65(3): 281-282
DOI: 10.1055/s-2006-960780

Letter

Isolation and Identification of a New Antifungal Sesquiterpene Lactone from Inula viscosa

Michal Maoz¹ ^, ³ , Yoel Kashman² , Ishak Neeman¹

¹Department of Food Engineering and Biotechnology, Technion, Haifa, Israel
²School of Chemistry, Tel Aviv University, Tel Aviv, Israel
³Department of Biotechnology, Braude Technology College, Carmiel, Israel

Abstract

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Abstract

A new sesquiterpene - tayunin - has been isolated and purified from powdered leaves of Inula viscosa (L.) Ait. The chemical structure was determined by 1D and 2D NMR analysis, and IR and MS. Tayunin inhibits the growth of Microsporum canis at a concentration of 10 µg/ml and Trichophyton rubrum at 50 µg/ml(MIC).

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