Chemical Analysis and Antimicrobial Activity of the Resin Ladano, of its Essential Oil and of the Isolated Compounds**

Costas Demetzos; Berthamarie Stahl; Thalia Anastassaki; Maria Gazouli; Leonidas S. Tzouvelekis; Michalis Rallis

doi:10.1055/s-2006-960444

Planta Med 1999; 65(1): 76-78
DOI: 10.1055/s-2006-960444

Letter

Chemical Analysis and Antimicrobial Activity of the Resin Ladano, of its Essential Oil and of the Isolated Compounds**

Costas Demetzos¹ , Berthamarie Stahl¹ , Thalia Anastassaki¹ , Maria Gazouli² , Leonidas S. Tzouvelekis² , Michalis Rallis³

¹Dept. of Pharmacy, Lab. of Pharmacognosy, University of Athens, Greece
²Dept. of Bacteriology, Hellenic Pasteur Institute, Athens, Greece
³Dept. of Pharmaceutical Technology, School of Pharmacy, University of Athens, Greece

** A part of this paper was presented as a poster at the 45th Annual Congress on Medicinal Plant Research, Regensburg, Sept. 7-12, 1997.

Abstract

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Abstract

Fractionation of the resin Ladano from Cistus creticus subsp. creticus and susceptibility testing using the chromatographic fractions showed that its antistaphylococcal activity was mainly due to the diterpene sclareol. The antimicrobial activity of its essential oil, of the chromatographic fractions, and of the isolated compounds was also evaluated against Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus hominis.

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