© Georg Thieme Verlag Stuttgart · New York
6-Pentadecylsalicylic Acid; An Antithrombin Component Isolated from the Stem of Rhus semialata varroxburghii
05 January 2007 (online)
Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 µg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.
6-Pentadecylsalicylic acid - antithrombin - amidolytic method - clotting time - lanatebulic acid - Rhus semialata