Planta Med 1991; 57(2): 184-186
DOI: 10.1055/s-2006-960062

© Georg Thieme Verlag Stuttgart · New York

Iridoid Glucosides from Penstemon nitidus

Dirk Teborg, Peter Junior
  • Institut für Pharmazeutische Biologie der Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, D-4000 Düsseldorf 1, Federal Republic of Germany
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Publication History


Publication Date:
05 January 2007 (online)


From the leaves of Penstemon nitidus Dougl. (smooth blue beardtongue) besides the known iridoid glucosides cornin (syn. verbenalin), hastatoside and β-dihydrohastatoside the new compound 10-hydroxycornin has been isolated. The structures of all compounds were established by spectroscopic means (FD-MS, 1H-, 13C-, 2D-NMR, and NOE). This is the first report of cornin and analogous 6-keto iridoids in scrophulariaceous plants. Up to now iridoid glucosides like these have only been found in plants belonging to the Cornaceae and its allies and to the Lamiaceae-Verbenaceae complex.