Planta Med 1991; 57(2): 176-180
DOI: 10.1055/s-2006-960060

© Georg Thieme Verlag Stuttgart · New York

Qualitative and Quantitative Analysis of the Phenolic Constituents from Orthosiphon aristatus

Wahono Sumaryono1 , 2 , Peter Proksch1 , Victor Wray3 , Ludger Witte1 , Thomas Hartmann1
  • 1Institut für Pharmazeutische Biologie, TU Braunschweig, Mendelssohnstr.1, D-3300 Braunschweig, Federal Republic of Germany
  • 2Directorate of Life Sciences, Agency for the Assessment and Application of Technology (B.P.P. Teknologi), Jl. M. H. Thamrin 8, Jakarta Pusat 10340, Indonesia
  • 3Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig, Federal Republic of Germany
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Publication History


Publication Date:
05 January 2007 (online)


Orthosiphon aristatus (Orthosiphonis folium DAB 9) was studied with regard to its phenolic constituents. Twenty compounds were isolated and identified on the basis of their spectral characteristics. The compounds included nine lipophilic flavones, two flavonol glycosides, and nine caffeic acid derivatives. The presence of the recently reported methylripariochromene A could not be confirmed. All compounds identified were quantified by HPLC. The caffeic acid derivatives including the major compounds rosmarinic acid and 2,3-dicaffeoyltartaric acid (67% of total identified phenolics) predominated over the flavones (33%) in an aqueous MeOH extract. The predominance of the caffeic acid derivatives was even more pronounced in a hot water extract (94.5% of total identified phenolics) that was comparable to a herbal tea.