© Georg Thieme Verlag Stuttgart · New York
4-Hydroxy-2-cyclopentenone: An Anti-Pseudomonas and Cytotoxic Component from Passiflora tetrandra 11 Antibiotic Compounds from New Zealand Plants; Part IV.
05 January 2007 (online)
4-Hydroxy-2-cyclopentenone is responsible for the anti-bacterial activity of an extract of leaves from Passiflora tetrandra with minimum inhibitory doses (MID) of ca. 10 µg/disk against Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa. 4-Hydroxy-2-cyclopentenone is also cytotoxic to P388 murine leukemia cells (IC50 of < 1 µg/ml).
Passiflora tetrandra - Passifloraceae - 4-hydroxy-2-cyclopentenone - anti-pseudomonad - cytotoxic