Immunologically Active Polysaccharide from Cetraria islandica

Kristin Ingolfsdottir; Ksenija Jurcic; Bettina Fischer; Hildebert Wagner

doi:10.1055/s-2006-959564

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml

Share / Bookmark

Facebook X Linkedin Weibo

Download PDF

Planta Med 1994; 60(6): 527-531
DOI: 10.1055/s-2006-959564

Papers

Immunologically Active Polysaccharide from Cetraria islandica

Kristin Ingolfsdottir¹ , Ksenija Jurcic² , Bettina Fischer² , Hildebert Wagner²

¹Department of Pharmacy, University of Iceland, S-101 Reykjavik, Iceland
²Institut für Pharmazeutische Biologie der Universität München, Karlstraße 29, D-80333 München, Federal Republic of Germany

Further Information

Publication History

1993

1994

Publication Date:
05 January 2007 (online)

PDF Download Permissions and Reprints

Abstract

A new alkali-soluble polysaccharide has been isolated from Iceland moss, Cetraria islandica (L.) Ach., by ethanol fractionation, ion-exchange chromatography, and gel filtration. The mean M_r was estimated to be 18,000. Sugar and methylation analysis, partial hydrolysis, and ¹³C-NMR spectroscopy showed the polysaccharide to be a branched galactomannan with a backbone composed of two structural elements; (1→6)-linked α-D-mannopyranosyl and α-D-(1→6)-galactopyranosyl units. The polysaccharide showed pronounced immunostimulating activity in an in vitro phagocytosis assay and in the in vivo carbon clearance assay.

Key words

Cetraria islandica - Parmeliaceae - Iceland moss - galactomannan - plant polysaccharide - immunological activity

>