Planta Med 1994; 60(4): 360-364
DOI: 10.1055/s-2006-959501

© Georg Thieme Verlag Stuttgart · New York

Caffeoylquinic Acids and Some Biological Activities of Pluchea symphytifolia

E. Scholz1 , M. Heinrich1 , D. Hunkler2
  • 1Institut für Pharmazeutische Biologie der Universität, Schänzlestr. 1, D-79104 Freiburg/B., Federal Republic of Germany
  • 2Institut für Organische Chemie und Biochemie der Universität, Albertstr. 21, D-79104 Freiburg/B., Federal Republic of Germany
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Publication History



Publication Date:
04 January 2007 (online)


From the aerial parts of Pluchea symphytifolia, four known and two new caffeoylquinic acids, 1,3,4,5-tetra-O-caffeoylquinic acid and 1,3-di-O-[3,4-bis-(3,4-dihydroxyphenyl)-cyclobutane-1,2-dicarbonyl]-4,5-di-O-caffeoylquinic acid, and two flavonols were isolated and their structures elucidated by mass and NMR spectroscopy and by chemical degradation. The aqueous extract had weak antibacterial and weak antisecretory effects; the lipophilic extract showed a modest anthelmintic activity. The higher caffeoylated quinic acids participated in the antibacterial and anthelmintic effect of the extracts.