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Planta Med 1994; 60(2): 118-120
DOI: 10.1055/s-2006-959430
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© Georg Thieme Verlag Stuttgart · New York

Antiulcer Action of Styrax camporum and Caesalpinia ferrea in Rats

Elfriede Marianne Bacchi1 , Jayme Antonio Aboin Sertié2
  • 1Departamento de Farmácia da Faculdade de Ciências Farmacêuticas da Universidade de São Paulo Caixa Postal 66083, CEP 05389-970 São Paulo, SP Brasil
  • 2Laboratório de Farmacologia e Toxicologia de Produtos Naturais, Departamento de Farmacologia, Instituto de Ciências Biomédicas da Universidade de São Paulo, São Paulo, SP Brasil
Further Information

Publication History

1993

1993

Publication Date:
04 January 2007 (online)

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Abstract

Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both extracts, atropine, and Cimetidine. After oral administration there was a decrease in the gastric secretion volume without modification of the other gastric secretion parameters studied. There were modifications, however, when the extracts were administered intraperitoneally. Analgesy, influence on sleeping time, and spontaneous motor activity test results indicate a probable absence of central action components in the extracts.

Key words

Styrax camporum Pohl - Styraceae - Caesalpinia ferrea Martius - Leguminosae - antiulcer action

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