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© Georg Thieme Verlag Stuttgart · New York
Cytotoxic and Antibacterial Labdane-Type Diterpenes from the Aerial Parts of Cistus incanus subsp. creticus
04 January 2007 (online)
Seven labdane-type diterpenoids were isolated from the leaves of Cistus incanus subsp. creticus; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against three cell line systems: KB, P-388; and NSCLC-N6. Their antibacterial and anti-fungal activities were tested against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosae, Enterobacter cloacae, Escherichia coli, Klebsiella pneumonia, Torulopsis glabrata, Saccharomyces cerevisiae, and Candida albicans as well.
Cistus - Cistaceae - labdane diterpenes - cytotoxicity - antibacterial activity