Abstract
On oral administration of onion {Allium cepa L.) and garlic (A. sativum L.) sulfoxide amino acids viz., S-methylcysteine sulfoxide (SMCS) and S-allylcysteine sulfoxide (SACS) to alloxan-diabetic rats for a month, their diabetic
condition, being characterized by glucose intolerance, weight loss, depletion of liver
glycogen, etc., was ameliorated as comparable to rats treated with glibenclamide and
insulin. However, only the last two drugs significantly increased the conversion of
labelled acetate to liver cholesterol which indicates a deterrent effect of the allium
products against the synthesis of a risk factor.
