Tannins with Antimutagenic Properties in the Herb of Alchemilla Species and Potentilla anserina*

Oskar Schimmer; Monika Lindenbaum

doi:10.1055/s-2006-958034

Planta Medica, Table of Contents

Planta Med 1995; 61(2): 141-145
DOI: 10.1055/s-2006-958034

Papers

Tannins with Antimutagenic Properties in the Herb of Alchemilla Species and *Potentilla anserina**

Oskar Schimmer, Monika Lindenbaum

Institut für Botanik und Pharmazeutische Biologie der Universität Erlangen-Nürnberg, Staudtstraße 5, D-91058 Erlangen, Germany

* Dedicated to Prof. Dr. F.-C. Czygan, University of Würzburg, on the occasion of his 60th birthday.

Abstract

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Abstract

Self-prepared ethanolic and aqueous extracts and commercial tinctures derived from the herb of Alchemilla spec. and Potentilla anserina were compared for their antimutagenic potency using 2-nitrofluorene as standard mutagen. All samples studied showed weak or moderate activities. The total amount of tannins did not correlate well with the degree of inhibition. However, tannin-free extracts did not display any inhibition of mutagenicity. Therefore, the tannin fraction participates at least partly in the antimutagenicity of the extracts examined.

Key words

Tannins - ellagic acid - antimutagenicity - Alchemilla mollis - Alchemilla alpina - Potentilla anserina - Rosaceae

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