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Planta Med 1996; 62(6): 565-566
DOI: 10.1055/s-2006-957974
Letters

© Georg Thieme Verlag Stuttgart · New York

Sesquiterpene Peroxides from Senecio selloi and Eupatorium rufescens 1

G. Rücker2 , E. P. Schenkel3 , D. Manns2 , R. Mayer2 , K. Heiden2 , B. M. Heinzmann2
  • 2Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, D-53115 Bonn, Germany
  • 3Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto Alegre, RS, Brazil
1 Part 21 in the series “Peroxides as Constituents of Plants”. For Part 20 see ref. (1)
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1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

Two bisabolane-type sesquiterpenes, zingiberene-3,6-β-endoperoxide (1) and zingiberene-3,6-α-endoperoxide (2) have been isolated from the aerial parts of Senecio selloi and Eupatorium rufescens. Their structures were determined by spectroscopic methods. Both compounds show schizonticidal activity against Plasmodium falciparum (EC50 = 10 µg/ml).