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Planta Med 1996; 62(6): 534-539
DOI: 10.1055/s-2006-957964
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© Georg Thieme Verlag Stuttgart · New York

Constituents of Veltheimia viridifolia; I. Homoisoflavanones of the Bulbs*

Gudrun Amschler1 , August W. Frahm1 , Armin Hatzelmann2 , Ulrich Kilian2 , Dieter Müller-Doblies3 , Ulrike Müller-Doblies3
  • 1Lehrstuhl für Pharmazeutische Chemie der Universität Freiburg, Hermann-Herder-Str. 9, D-79104 Freiburg i. Br., Germany
  • 2Byk Gulden Pharmaceuticals, Department of Biochemistry/Pharmacology, Byk-Gulden-Str. 2, D-78467 Konstanz, Germany
  • 3Herbarium BTU, Institut für Biologie, Fachbereich 14, Technische Universität Berlin, Franklin Str. 28-29, D-10587 Berlin, Germany
* Dedicated to Prof. Dr. Drs. h.c. H. Oelschläger on the occassion of 75th anniversary of his birthday.
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Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

The new homoisoflavanone R(-)-3-(4-hydroxybenzyl)-5-hydroxy-6,7,8-trimethoxychroman-4-one (1) was isolated from the petroleum ether and the diethyl ether extracts of the bulbs of Veltheimia viridifolia (Hyacinthaceae) together with the known homoisoflavanone muscomin (2). The structures of the compounds were elucidated by means of 1H-NMR, 2D 1H-1H-COSY, 13C-NMR, HMQC, HMBC, mass, and CD spectra. Pharmacological testings of the new homoisoflavanone are reported.

Key words

Veltheimia viridifolia - Hyacinthaceae - homoisoflavanones - phosphodiesterase inhibitor activity