Planta Med 1997; 63(6): 556-558
DOI: 10.1055/s-2006-957765

© Georg Thieme Verlag Stuttgart · New York

Antispasmodic and Spasmogenic Effects of Scolymus hispanicus and Taraxasteryl Acetate on Isolated Ileum Preparation

Neş'e Kirimer1 , Zeynep Tunalier1 , K. Hüsnü Can Başer1 , Ipek Cingi2
  • 1Anadolu University, Medicinal and Aromatic Plant and Drug Research Centre (TBAM), TR-26470 Eskişehir, Turkey
  • 2Osmangazi University, Faculty of Medicine, Department of Pharmacology, TR-26040 Eskişehir, Turkey
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Publication History



Publication Date:
04 January 2007 (online)


Taraxasteryl acetate (1) was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L. Antispasmodic and spasmogenic effects of the ethanolic extract, its fractions, taraxasteryl acetate, and a fluid extract of this plant were tested on isolated rat ileum preparations. The strong biphasic responses observed suggested a possible lithuretic activity of the compounds and the fractions tested.