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Planta Med 1997; 63(6): 533-535
DOI: 10.1055/s-2006-957757
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Biochemistry, Physiology, in vitro Cultures
© Georg Thieme Verlag Stuttgart · New York

Biosynthesis of Isonorargemonine, Eschscholtzidine and 4-Hydroxyeschscholtzidine in Thalictrum minus

Atanas K. Sidjimov
  • Faculty of Chemistry, University of Sofia, 1 James Bourchier Avenue, 1126 Sofia, Bulgaria
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Publication History

1997

1997

Publication Date:
04 January 2007 (online)

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Abstract

Feeding experiments with 14 C-labelled reticuline have shown that reticuline is an efficient precursor of isonorargemonine, eschscholtzidine, and 4-hydroxyeschscholtzidine in Thalictrum minus (Ranunculaceae). Feeding experiments using 14 C-labelled isonorargemonine and eschscholtzidine led to the conclusion that the substitution pattern of 4-hydroxyeschscholtzidine can be formed at the pavine stage.

Key words

Thalictrum minus - Ranunculaceae - biosynthesis - alkaloids - reticuline - isonorargemonine - eschscholtzidine - 4-hydroxyeschscholtzidine