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Planta Med 1997; 63(4): 374-376
DOI: 10.1055/s-2006-957709
Letters

© Georg Thieme Verlag Stuttgart · New York

Erythroxan Diterpenes from Fagonia glutinosa

Maged S. Abdel-Kader1 , Abdallah A. Omar1 , Frank R. Stermitz2
  • 1Department of Pharmacognosy, College of Pharmacy, University of Alexandria, Alexandria, Egypt
  • 2Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, U.S.A.
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Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

Further investigation of the ether extract of the aerial parts of Fagonia glutinosa utilizing the brine shrimp bioassay resulted in the isolation of two new cytotoxic erythroxan diterpenes: 1α,10α-epoxy-2-oxofagonene (1) and 1β,10β-epoxy-2-oxofagonene (2). In addition, two inactive diterpenes, 2-oxofagonene (3) and its previously reported isomer 2-oxo-5-epi-fagonene (4), were also isolated.