Protective Effect of Curcuminoids on Epidermal Skin Cells under Free Oxygen Radical Stress

Frédéric Bonté; Marie-Sophie Noel-Hudson; J. Wepierre; A. Meybeck

doi:10.1055/s-2006-957669

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Planta Med 1997; 63(3): 265-266
DOI: 10.1055/s-2006-957669

Letters

Protective Effect of Curcuminoids on Epidermal Skin Cells under Free Oxygen Radical Stress

Frédéric Bonté¹ , Marie-Sophie Noel-Hudson² , J. Wepierre² , A. Meybeck¹

¹LVMH Recherche, 25 L rue des Peupliers, F-92752 Nanterre, France
²Laboratoire de Pharmacologie, Faculté de Pharmacie Université Paris Sud, rue J. B Clément, F-92290 Chatenay-Malabry, France

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1996

1996

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

Curcuminoids from Curcuma longa L. (Zingiberaceae) protected normal human keratinocytes from hypoxanthine/ xanthine oxidase injury. Since curcuminoids synergistically inhibited nitroblue tetrazolium reduction, a decrease in superoxide radical formation leading to lower levels of cytotoxic hydrogen peroxide was proposed as an explanation for this protective effect.

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