© Georg Thieme Verlag Stuttgart · New York
Protective Effect of Curcuminoids on Epidermal Skin Cells under Free Oxygen Radical Stress
04 January 2007 (online)
Curcuminoids from Curcuma longa L. (Zingiberaceae) protected normal human keratinocytes from hypoxanthine/ xanthine oxidase injury. Since curcuminoids synergistically inhibited nitroblue tetrazolium reduction, a decrease in superoxide radical formation leading to lower levels of cytotoxic hydrogen peroxide was proposed as an explanation for this protective effect.