Antinociceptive Components of Ganoderma lucidum

Kiyotaka Koyama; Tooru Imaizumi; Michiko Akiba; Kaoru Kinoshita; Kunio Takahashi; Akira Suzuki; Shingo Yano; Syunji Horie; Kazuo Watanabe; Yukio Naoi

doi:10.1055/s-2006-957658

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Planta Med 1997; 63(3): 224-227
DOI: 10.1055/s-2006-957658

Papers

Pharmacology and Molecular Biology
© Georg Thieme Verlag Stuttgart · New York

Antinociceptive Components of Ganoderma lucidum

Kiyotaka Koyama¹ , Tooru Imaizumi¹ , Michiko Akiba¹ , Kaoru Kinoshita¹ , Kunio Takahashi¹ , Akira Suzuki² , Shingo Yano³ , Syunji Horie³ , Kazuo Watanabe³ , Yukio Naoi⁴

¹Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy, 1-22-1 Yato-cho, Tanashi-shi, Tokyo 188, Japan
²Faculty of Education, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263, Japan
³Faculty of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263, Japan
⁴Kojoen Co., Ltd., 1 -12, Gokasho Hirookadani, Uji-shi, Kyoto 611, Japan

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Publikationsverlauf

1996

1996

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

The antinociceptive effects 134 extracts prepared from 45 species of mushrooms were examined by the acetic acid-induced writhing method. From the CH₂Cl₂ extract of Ganoderma lucidum among the active extracts, ganoderic acids A, B, G and H and compound C6 were isolated as the antinociceptive components.

key words

Ganodema lucidum - Ganodermataceae - mushrooms - Basidiomycetes - Ascomycetes - antinociceptive - triterpenoids

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