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© Georg Thieme Verlag Stuttgart · New York
Torilin, a Sesquiterpene from Torilis japonica, Reverses Multidrug-Resistance in Cancer Cells
04 January 2007 (online)
A sesquiterpene compound reversing multidrug-resistance in cancer cells was isolated from the fruits of Torilis japonica and the structure was identified as torilin. Torilin potentiated the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells.
Torilis japonica - Umbelliferae - torilin - sesquiterpene - multidrug-resistance (MDR)