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Planta Med 1998; 64(3): 242-245
DOI: 10.1055/s-2006-957418
DOI: 10.1055/s-2006-957418
Papers
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York
A New Epimeric Pair of Mono-THF Annonaceous Acetogenins from Goniothalamus gardneri
Further Information
Publication History
1997
1997
Publication Date:
04 January 2007 (online)
Abstract
From the roots of Goniothalamus gardneri Hook f. et. Thoms (Annonaceae), we have isolated a novel epimeric pair, gardnerinin (1) and 34-epi-gardnerinin (1′), characterized by the presence of a γ-hydroxymethyl-γ-lactone moiety. These compounds represent an unusual type of mono-THF Annonaceous acetogenins, bearing one flanking hydroxy group on the hydrocarbon side, and another hydroxy group on the lactone side, that is only one carbon away from the THF ring.
Key words
Goniothalamus gardneri - Annonaceae - acetogenin - gardnerinin - 34-epi-gardnerinin