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Planta Med 1998; 64(1): 79-80
DOI: 10.1055/s-2006-957375
Letters

© Georg Thieme Verlag Stuttgart · New York

Sesquiterpenes, Limonoid and Coumarin from the Wood Bark of Guarea guidonia

Fernanda R. Garcez1 , Cecília V. Núñez2 , Walmir S. Garcez1 , Rene M. Almeida1 , Nidia F. Roque2
  • 1Universidade Federal de Mato Grosso do Sul, Departamento de Química, Campo Grande, Brazil
  • 2Universidade de São Paulo, Institute de Química, São Paulo, Brazil
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Publication History

1997

1997

Publication Date:
04 January 2007 (online)

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Abstract

Investigation of the wood bark of Guarea guidonia (Meliaceae) led to the isolation of a limonoid (mombasol), a coumarin (scopoletin), and six sesquiterpenes [trans-1(10)-epoxy-4(15)-caryophyllene, 1(10)-epoxy-4,7-humuladiene, viridiflorol, 1(10),4-diepoxy-7-humulene, 3-oxo-10-alloaromadendranol, 1β-6α-dihydroxyeudesm-4(15)ene]. The occurrence of these metabolites in the Guarea genus is reported for the first time. Stigmasterol, sitosterol and its oleate and palmitate esters were also obtained. Some corrections to the previously reported chemical shift assignments of 3-oxo-10-alloaromadendranol (13C-NMR) were made.