Sesquiterpenes, Limonoid and Coumarin from the Wood Bark of Guarea guidonia

Fernanda R. Garcez; Cecília V. Núñez; Walmir S. Garcez; Rene M. Almeida; Nidia F. Roque

doi:10.1055/s-2006-957375

Planta Medica, Table of Contents

Planta Med 1998; 64(1): 79-80
DOI: 10.1055/s-2006-957375

Letters

Sesquiterpenes, Limonoid and Coumarin from the Wood Bark of Guarea guidonia

Fernanda R. Garcez¹ , Cecília V. Núñez² , Walmir S. Garcez¹ , Rene M. Almeida¹ , Nidia F. Roque²

¹Universidade Federal de Mato Grosso do Sul, Departamento de Química, Campo Grande, Brazil
²Universidade de São Paulo, Institute de Química, São Paulo, Brazil

Abstract

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Abstract

Investigation of the wood bark of Guarea guidonia (Meliaceae) led to the isolation of a limonoid (mombasol), a coumarin (scopoletin), and six sesquiterpenes [trans-1(10)-epoxy-4(15)-caryophyllene, 1(10)-epoxy-4,7-humuladiene, viridiflorol, 1(10),4-diepoxy-7-humulene, 3-oxo-10-alloaromadendranol, 1β-6α-dihydroxyeudesm-4(15)ene]. The occurrence of these metabolites in the Guarea genus is reported for the first time. Stigmasterol, sitosterol and its oleate and palmitate esters were also obtained. Some corrections to the previously reported chemical shift assignments of 3-oxo-10-alloaromadendranol (¹³C-NMR) were made.

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