5α-Cardenolides from Kanahia laniflora Inhibit Ionotropic Acetylcholine Receptors

Abstract

5α-Cardenolides isolated from Kanahia laniflora are inhibitors of muscle-type nicotinic acetylcholine receptors expressed in TE671 cells with IC₅₀ values in the range of 27 - 60 μM, as determined by whole-cell patch-clamp electrophysiological experiments.

References

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