Cosmetic applications of selected Various Citrus fruits

Because tyrosinase catalyzes melanin synthesis, tyrosinase inhibitors are important in cosmetic skin-whitening. Oxidative stress contributes to skin aging and can adversely affect skin health, which means antioxidants active in skin cells may support skin health.

Total 50 citrus species involved jeju citrus fruits 17 species were cultivated in Jeju-island (in South Korea). And Citrus Unshiu is the most cultivated with compared other species of citrus in Jeju-island. We examined traditional citrus 17 species that might be useful for skin-whitening and skin health. Extracts (50g/mL) were tested for cytotoxicity on B16 melanoma cells; 17 exhibited low cytotoxicity. Their effects on tyrosinase and melanin inhibitory activities and free radical scavenging activities were further assessed. Three Citrus fruits, Immature Citrus unshiu Marc., Citrus hassaku Hort. ex Tanaka and Citrus sinensis×reticulata exhibited potent inhibitory effects on melanin formation. Immature Citrus unshiu, Citrus hassaku, and Citrus sinensis×reticulata showed good antioxidative activities. Among active making them the strongest candidates for cosmetic application found in the current study.

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