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Semin Speech Lang 2006; 27(3): 143-160
DOI: 10.1055/s-2006-948226
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Early Identification of Autism: How Early Can We Go?

Elizabeth R. Crais1 , 5 , Linda R. Watson2 , 5 , Grace T. Baranek3 , 5 , J. Steven Reznick4 , 5
  • 1Professor, Division of Speech and Hearing Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • 2Associate Professor, Division of Speech and Hearing Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • 3Associate Professor, Division of Occupational Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • 4Professor, Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • 5University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
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Publikationsdatum:
29. August 2006 (online)

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ABSTRACT

Identification of young children at risk for Autism Spectrum Disorders (ASD) depends on early behavioral symptomatology and yet conventional criteria provide little guidance for use with infants and toddlers. Recent research, however, has demonstrated that there are patterns of behavior below 2 years of age that distinguish children with autism from those who are developing typically or those with other developmental disabilities. Skill areas with particular promise for early identification include social communication, sensory regulation, and play. This article previews current innovative methodologies, presents a synthesis of recent research findings related to these three key areas, and provides clinicians with practical guidelines for early identification of infants and toddlers at risk for ASD and other disorders.

KEYWORDS

Autism spectrum disorders - infants and toddlers - early identification

REFERENCES

  • 1 Centers for Disease Control and Prevention . Mental health in the United States: parental report of diagnosed autism in children aged 4-17 years-United States, 2003-2004.  MMWR Morb Mortal Wkly Rep. 2006;  55 481-486
    PubMedGoogle Scholar
  • 2 National Research Council .Educating Children with Autism. Washington, DC; National Academy Press 2001
    Google Scholar
  • 3 Individuals with Disabilities Education Improvement Act of 2004, 34 CFR §300.7 (2004)
    Google Scholar
  • 4 Gernsbacher M, Dawson M, Goldsmith H. Three reasons to believe in an autism epidemic.  Current Directions in Psychological Sciences. 2004;  32 373-396
    PubMedGoogle Scholar
  • 5 Chakrabarti S, Fombonne E. Pervasive developmental disorders in preschool children.  JAMA. 2001;  285 3093-3099
    CrossrefPubMedGoogle Scholar
  • 6 Filipek P A, Accardo P J, Baranek G T et al.. The screening and diagnosis of autistic spectrum disorders.  J Autism Dev Disord. 1999;  29 439-484
    CrossrefPubMedGoogle Scholar
  • 7 Mandell D, Novak M, Zubritsky C. Factors associated with age of diagnosis among children with autism spectrum disorders.  Pediatrics. 2005;  116 1480-1486
    CrossrefPubMedGoogle Scholar
  • 8 Fenske E, Zalenski S, Krantz P, McClannahan L. Age at intervention and treatment outcome for autistic children in a comprehensive intervention program.  Analysis and Intervention for Developmental Disabilities. 1985;  5 49-58
    PubMedGoogle Scholar
  • 9 Harris S, Handleman J. Age and IQ at intake as predictors of placement for young children with autism: a four- to six-year follow-up.  J Autism Dev Disord. 2000;  30 137-142
    PubMedGoogle Scholar
  • 10 McGee G, Morrier M, Daly T. An incidental teaching approach to early intervention for toddlers with autism.  J Assoc Pers Sev Handicaps. 1999;  24 133-146
    PubMedGoogle Scholar
  • 11 De Giacomo A, Fombonne E. Parental recognition of developmental abnormalities in autism.  Eur Child Adolesc Psychiatry. 1998;  7 131-136
    CrossrefPubMedGoogle Scholar
  • 12 Siegel B, Pliner C, Eschler J, Elliott G R. How children with autism are diagnosed: difficulties in the identification of children with multiple developmental delays.  J Dev Behav Pediatr. 1988;  9 199-204
    PubMedGoogle Scholar
  • 13 Schall C. Family perspectives on raising a child with autism.  J Child Fam Stud. 2000;  9 409-423
    CrossrefPubMedGoogle Scholar
  • 14 American Psychiatric Association .Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC; American Psychiatric Association 2000
    Google Scholar
  • 15 Baranek G. Autism during infancy: a retrospective video analysis of sensory-motor and social behaviors at 9-12 months of age.  J Autism Dev Disord. 1999;  29 213-224
    PubMedGoogle Scholar
  • 16 Symons F, Sperry L, Dropik P, Bodfish J. The early development of stereotypy and self-injury: a review of research methods.  J Intellect Disabil Res. 2005;  49 144-158
    CrossrefPubMedGoogle Scholar
  • 17 Thelen E. Rhythmical behavior in infancy: an ethological perspective.  Dev Psychol. 1981;  17 237-257
    CrossrefPubMedGoogle Scholar
  • 18 Lord C. Follow-up of two-year-olds referred for possible autism.  J Child Psychol Psychiatry. 1995;  36 1365-1382
    PubMedGoogle Scholar
  • 19 Stone W L, Lee E B, Ashford L et al.. Can autism be diagnosed accurately in children under three years?.  J Child Psychol Psychiatry. 1999;  40 219-226
    CrossrefPubMedGoogle Scholar
  • 20 Rutter M, LeCouteur A, Lord C. Manual for the Autism Diagnostic Interview. Rev Los Angeles, CA; Western Psychological Services 2003
  • 21 Stone W, Coonrod E, Ousley O. Brief report: screening tool for autism in two-year-olds (STAT): development and preliminary data.  J Autism Dev Disord. 2000;  30 607-612
    PubMedGoogle Scholar
  • 22 Baird G, Charman T, Baron-Cohen S et al.. A screening instrument for autism at 18 months of age: a 6-year follow-up study.  J Am Acad Child Adolesc Psychiatry. 2000;  39 694-702
    PubMedGoogle Scholar
  • 23 Baron-Cohen S, Allen J, Gillberg C. Can autism be detected at 18 months? The needle, the haystack, and the CHAT.  Br J Psychiatry. 1992;  161 839-843
    PubMedGoogle Scholar
  • 24 Baron-Cohen S, Cox A, Baird G et al.. Psychological markers in the detection of autism in infancy in a large population.  Br J Psychiatry. 1996;  168 158-163
    CrossrefPubMedGoogle Scholar
  • 25 Charman T, Swettenham B, Cox A, Baird G, Drew A. An experimental investigation of social-cognitive abilities in infants with autism: clinical implications.  Infant Ment Health J. 1998;  19 260-275
    CrossrefPubMedGoogle Scholar
  • 26 Robins D, Fein D, Barton M, Greene J. The Modified Checklist for Autism in Toddlers: an initial study investigating the early detection of autism and pervasive developmental disorders.  J Autism Dev Disord. 2001;  31 131-144
    CrossrefPubMedGoogle Scholar
  • 27 Wing L. The handicaps of autistic children-a comparative study.  J Child Psychol Psychiatry. 1969;  10 1-40
    PubMedGoogle Scholar
  • 28 Dahlgren S O, Gillberg C. Symptoms in the first two years of life.  Euro Arch Psychiatry Neurol Sci. 1989;  238 169-174
    PubMedGoogle Scholar
  • 29 Stone W, Lemanek K. Parental report of social behaviors in autistic preschoolers.  J Autism Dev Disord. 1990;  20 513-522
    PubMedGoogle Scholar
  • 30 Vostanis P, Smith B, Corbett J et al.. Parental concerns of early development in children with autism and related disorders.  Autism. 1998;  2 229-242
    PubMedGoogle Scholar
  • 31 Wimpory D C, Hobson R P, Williams J MG, Nash S. Are infants with autism socially engaged? A study of recent retrospective parental reports.  J Autism Dev Disord. 2000;  30 525-536
    PubMedGoogle Scholar
  • 32 Zwaigenbaum L, Bryson S, Rogers T, Roberts W, Brian J, Szatmari P. Behavioral manifestations of autism in the first year of life.  Int J Dev Neurosci. 2005;  23 143-152
    PubMedGoogle Scholar
  • 33 Yirmiya N, Gamliel I, Pilowsky T, Feldman R, Baron-Cohen S, Sigman M. The development of siblings of children with autism at 4 and 14 months: social engagement, communication, and cognition.  J Child Psychol Psychiatry. 2006;  47 511-523
    CrossrefPubMedGoogle Scholar
  • 34 Szatmari P, Jones M, Zwaigenbaum L, MacLean J. Genetics of autism: overview and new directions.  J Autism Dev Disord. 1998;  28 351-368
    PubMedGoogle Scholar
  • 35 Bayley N. Bayley Scales of Infant Mental Development-Revised. 2nd ed. New York, NY; Psychological Corp 1993
    Google Scholar
  • 36 Wetherby A, Woods J, Allen L, Cleary J, Dickinson H, Lord C. Early indicators of autism spectrum disorders in the second year of life.  J Autism Dev Disord. 2004;  34 473-493
    CrossrefPubMedGoogle Scholar
  • 37 Wetherby A, Prizant B. Communication and Symbolic Behavior Scales-Developmental Profile (CSBS-DP). First Normed Edition. Baltimore, MD; Paul H Brookes 2002
    Google Scholar
  • 38 Charman T, Baron-Cohen S, Swettenham J, Baird G, Drew A, Cox A. Predicting language outcome in infants with autism and pervasive developmental disorder.  Int Lang Commun Disord. 2003;  38 265-285
    PubMedGoogle Scholar
  • 39 Cox A, Klein K, Charman T et al.. Autism spectrum disorders at 20 and 42 months of age: stability of clinical and ADI-R diagnosis.  J Child Psychol Psychiatry. 1999;  40 719-732
    CrossrefPubMedGoogle Scholar
  • 40 Swettenham J, Baron-Cohen S, Charman T et al.. The frequency and distribution of spontaneous attention shifts between social and nonsocial stimuli in autistic, typically developing, and nonautistic developmentally delayed infants.  J Child Psychol Psychiatry. 1998;  39 747-753
    PubMedGoogle Scholar
  • 41 Lord C, Shulman C, DiLavore P. Regression and word loss in autistic spectrum disorders.  J Child Psychol Psychiatry. 2004;  45 936-955
    CrossrefPubMedGoogle Scholar
  • 42 Stone W, Coonrod E, Turner L, Pozdol S. Psychometric properties of the STAT for early autism screening.  J Autism Dev Disord. 2004;  34 691-701
    PubMedGoogle Scholar
  • 43 Dawson G, Osterling J, Meltzoff A, Kuhl P. Case study of the development of an infant with autism from birth to two years of age.  J Appl Dev Psychol. 2000;  21 299-313
    CrossrefPubMedGoogle Scholar
  • 44 Rutherford M. A retrospective journal-based case study of an infant with autism and his twin.  Neurocase. 2005;  11 129-137
    PubMedGoogle Scholar
  • 45 Sparling J. Brief report: a prospective case report of infantile autism from pregnancy to four years.  J Autism Dev Disord. 1991;  21 229-236
    PubMedGoogle Scholar
  • 46 Baranek G, Barnett C, Adams E, Wolcott N, Watson L, Crais E. Object play in infants with autism: methodological issues in retrospective video analysis.  Am J Occup Ther. 2005;  59 20-30
    PubMedGoogle Scholar
  • 47 Eriksson A S, de Chateau P. Brief report: a girl aged two years and seven months with autistic disorder videotaped from birth.  J Autism Dev Disord. 1992;  22 127-129
    PubMedGoogle Scholar
  • 48 Osterling J, Dawson G. Early recognition of children with autism: a study of first birthday home videotapes.  J Autism Dev Disord. 1994;  24 247-257
    CrossrefPubMedGoogle Scholar
  • 49 Osterling J A, Dawson G, Munson J A. Early recognition of 1-year-old infants with autism spectrum disorder versus mental retardation.  Dev Psychopathol. 2002;  14 239-251
    CrossrefPubMedGoogle Scholar
  • 50 Maestro S, Muratori F, Cristina Cavallaro M et al.. How young children treat objects and people: an empirical study of the first year of life in autism.  Child Psychiatry Hum Dev. 2005;  35 383-396
    CrossrefPubMedGoogle Scholar
  • 51 Neitzel J, Watson L, Baranek G, Crais E, Dysinger A, Wood S, Barry S. Gesture use in infants with autism at 9-12 and 15-18 months. Presented at: The Biennial Meeting of the Society for Research and Child Development April 24-27, 2003 Tampa, FL;
    Google Scholar
  • 52 Watson L, Baranek G, Crais E. Gesture development in infants with autism spectrum disorders. Presented at: Gatlinburg Conference on Theory and Research in Intellectual and Developmental Disabilities March 2005 Annapolis, MD;
    Google Scholar
  • 53 Watson L, Crais E, Baranek G, Roy V, Dykstra J. Longitudinal relations between play and gestures in infants with autism. Presented at: The American Speech-Language-Hearing Association Convention 2004 Philadelphia, PA;
    Google Scholar
  • 54 Reznick S, Baranek G, Reavis S, Watson L, Crais E. A parent-report instrument for identifying one-year olds at risk for an eventual diagnosis of autism: the first year inventory. http://Available from: bcrais@med.unc.edu July 2006
    Google Scholar
  • 55 Baranek G, Watson L, Crais E, Reznick J. The First Year Inventory. Unpublished instrument. Chapel Hill, NC; The University of North Carolina 2003 http://Available from: bcrais@med.unc.edu
    Google Scholar
  • 56 Gillberg C, Nordin V, Ehlers S. Early detection of autism: diagnostic instruments for clinicians.  Eur Child Adolesc Psychiatry. 1996;  5 67-74
    PubMedGoogle Scholar
  • 57 Ohta M, Nagai Y, Hara H et al.. Parental perception of behavioral symptoms in Japanese autistic children.  J Autism Dev Disord. 1987;  17 549-563
    PubMedGoogle Scholar
  • 58 Kurita H. Infantile autism with speech loss before the age of thirty months.  J Am Acad Child Psychiatry. 1985;  24 191-196
    PubMedGoogle Scholar
  • 59 Hoshino Y, Kumashiro H, Yashima Y, Tachibana R, Watanabe M, Furukawa H. Early symptoms of autistic children and its diagnostic significance.  Folia Psychiatr Neurol Jpn. 1982;  36 367-374
    PubMedGoogle Scholar
  • 60 Bernabei P, Camaioni L, Levi G. An evaluation of early development in children with autism and pervasive developmental disorders from home movies: preliminary findings.  Autism. 1998;  2 243-258
    PubMedGoogle Scholar
  • 61 Maestro S, Casella C, Milone A et al.. Study of the onset of autism through home movies.  Psychopathology. 1999;  32 292-300
    CrossrefPubMedGoogle Scholar
  • 62 Zakian A, Malvy J, Desombre H et al.. Early signs of autism and family films: a new study by informed evaluators and those unaware of the diagnosis.  Encephale. 2000;  26 38-44
    PubMedGoogle Scholar
  • 63 Adrien J L, Perrot A, Sauvage D et al.. Early symptoms in autism from family home movies: evaluation and comparison between 1st and 2nd year of life using I.B.S.E. scale.  Acta Paedopsychiatr. 1992;  55 71-75
    PubMedGoogle Scholar
  • 64 Mars A, Mauk J, Dowrick P. Symptoms of pervasive developmental disorders as observed in prediagnostic home videos of infants and toddlers.  J Pediatr. 1998;  132 500-504
    PubMedGoogle Scholar
  • 65 Rogers S, DiLalla D. Age of symptom onset in young children with pervasive developmental disorders.  J Am Acad Child Adolesc Psychiatry. 1990;  29 863-872
    PubMedGoogle Scholar
  • 66 Gillberg C, Ehlers S, Schaumann H et al.. Autism under age 3 years: a clinical study of 28 cases referred for autistic symptoms in infancy.  J Child Psychol Psychiatry. 1990;  21 921-934
    PubMedGoogle Scholar
  • 67 Adrien J, Martineau J, Perrot A, Hameury L, Larmande C, Sauvage D. Blind ratings of early symptoms of autism based upon family home movies.  J Am Acad Child Adolesc Psychiatry. 1993;  32 617-626
    PubMedGoogle Scholar
  • 68 Adrien J, Ornitz E, Barthelemy C, Savage D, Lelord G. The presence or absence of certain behaviors associated with infantile autism in severely retarded autistic and nonautistic retarded children and very young normal children.  J Autism Dev Disord. 1987;  17 407-416
    PubMedGoogle Scholar
  • 69 Greenspan S, Wieder S. Developmental patterns and outcomes in infants and children with disorders in relating and communicating: a chart review of 200 cases of children with autistic spectrum diagnoses.  J Dev Learn Disord. 1997;  1 87-141
    PubMedGoogle Scholar
  • 70 Carpenter M, Nagell K, Tomasello M. Social cognition, joint attention, and communicative competence from 9 to 15 months of age.  Monogr Soc Res Child Dev. 1992;  255(63)
    PubMedGoogle Scholar
  • 71 Crais E, Douglas D, Campbell C. The intersection of the development of gestures and intentionality.  J Speech Lang Hear Res. 2004;  47 678-694
    CrossrefPubMedGoogle Scholar
  • 72 Jones S E, Zimmerman D H. A child's point and the achievement of intentionality.  Gesture. 2003;  3 155-185
    PubMedGoogle Scholar
  • 73 Carpenter R, Mastergeorge A, Coggins T. The acquisition of communicative intentions in infants eight to fifteen months of age.  Lang Speech. 1983;  26 101-116
    PubMedGoogle Scholar
  • 74 Thal D, Tobias S. Communicative gestures in children with delayed onset of oral expressive vocabulary.  J Speech Hear Res. 1992;  35 1281-1289
    PubMedGoogle Scholar
  • 75 Saxon T, Frick J, Colombo J. A longitudinal study of maternal interactional styles and infant visual attention.  Merrill Palmer Q. 1997;  43 48-66
    PubMedGoogle Scholar
  • 76 Wetherby A, Cain D, Yonclas D, Walker V. Analysis of intentional communication of normal children from the prelinguistic to the multiword stage.  J Speech Hear Res. 1988;  31 240-252
    PubMedGoogle Scholar
  • 77 Wetherby A, Prizant B, Hutchinson T. Communicative, social/affective, and symbolic profiles of young children with autism and pervasive developmental disorders.  Am J Speech Lang Pathol. 1998;  7 79-91
    PubMedGoogle Scholar
  • 78 Ornitz E M, Guthrie D, Farley A H. The early development of autistic children.  J Autism Dev Disord. 1977;  7 207-229
    CrossrefPubMedGoogle Scholar
  • 79 Baranek G, Watson L, Crais E, Alcott K. Video analysis of gesture in infants with autism at 9-12 months. Presented at: The Society for Research in Child Development annual meeting 2001 Minneapolis, MN;
    Google Scholar
  • 80 Bruner J. The social context of language acquisition.  Lang Commun. 1981;  1 155-178
    CrossrefPubMedGoogle Scholar
  • 81 Coggins T, Mastergeorge A, Carpenter R. The acquisition of communicative intentions in infants eight to fifteen months of age.  Lang Speech. 1983;  26 101-116
    PubMedGoogle Scholar
  • 82 McEvoy R, Rogers S, Pennington R. Executive function and social communication deficits in young autistic children.  J Child Psychol Psychiatry. 1993;  34 563-578
    PubMedGoogle Scholar
  • 83 Mundy P, Crowson M. Joint attention and early social communication: implications for research on intervention with autism.  J Autism Dev Disord. 1997;  27 653-675
    PubMedGoogle Scholar
  • 84 Mundy P, Sigman M, Kasari C. Joint attention, developmental level, and symptom presentation in autism.  Dev Psychol. 1994;  6 389-401
    PubMedGoogle Scholar
  • 85 Mundy P. Joint attention and social-emotional approach behavior in children with autism.  Dev Psychopathol. 1995;  7 63-82
    PubMedGoogle Scholar
  • 86 Mundy P, Kasari C, Sigman M, Ruskin E. Nonverbal communication and early language acquisition in children with Down syndrome and in normally developing children.  J Speech Hear Res. 1995;  38 157-167
    PubMedGoogle Scholar
  • 87 Colgan S, Lanter L, McComish C, Watson L, Crais E, Baranek G. Analysis of social interaction gestures in infants with autism.  J Child Neuropsychol. 2006;  , In press
    PubMedGoogle Scholar
  • 88 Rollins P R, Wambacq I, Dowell D, Mathews L, Reese P B. An intervention technique for children with autistic spectrum disorder: joint attentional routines.  J Commun Disord. 1998;  31 181-193
    CrossrefPubMedGoogle Scholar
  • 89 Landry R, Bryson S E. Impaired disengagement of attention in young children with autism.  J Child Psychol Psychiatry. 2004;  45 1115-1122
    CrossrefPubMedGoogle Scholar
  • 90 Attwood A, Frith U, Hermelin B. The understanding and use of interpersonal gestures by autistic and Down's syndrome children.  J Autism Dev Disord. 1988;  18 241-257
    CrossrefPubMedGoogle Scholar
  • 91 Carpenter M, Pennington B, Rogers S. Interrelations among social-cognitive skills in young children.  J Autism Dev Disord. 2001;  32 91-106
    PubMedGoogle Scholar
  • 92 Wetherby A, Prutting C. Profiles of communicative and cognitive-social abilities in autistic children.  J Speech Hear Res. 1984;  27 364-377
    PubMedGoogle Scholar
  • 93 DiLavore P C, Lord C, Rutter M. The pre-linguistic autism diagnostic observation schedule.  J Aut Dev Disord. 1995;  25 355-379
    PubMedGoogle Scholar
  • 94 Fein D, Dunn M, Allen D et al.. Language and neuropsychological finding. In: Rapin L Preschool Children with Inadequate Communication. London, UK; Mac Keith 1996: 123-154
    Google Scholar
  • 95 Leekam S, Baron-Cohen S, Perrett D, Milders M, Brown S. Eye-direction detection: a dissociation between geometric and joint attention skills in autism.  British Journal of Developmental Psychology. 1997;  15(Pt 1) 77-95
    PubMedGoogle Scholar
  • 96 Leekam S, Hunnisett E, Moore C. Targets and cues: gaze-following in children with autism.  J Child Psychol Psychiatry. 1998;  39 951-962
    CrossrefPubMedGoogle Scholar
  • 97 Sigman M, Kasari C. Joint attention across contexts in normal and autistic children. In: Moore C, Dunham PJ Joint Attention: Its Origins and Role in Development. Hillsdale, NJ; Lawrence Erlbaum 1995: 189-203
    Google Scholar
  • 98 Baron-Cohen S, Baldwin D A, Crowson M. Do children with autism use the speaker's direction of gaze strategy to crack the code of language?.  Child Dev. 1997;  68 48-57
    PubMedGoogle Scholar
  • 99 Stone W, Ousley O, Littleford C. A comparison of elicited imitation in young children with autism and developmental delay. Presented at: The Gatlinburg Conference on Research and Theory of Mental Retardation 1995 Gatlinburg, TN;
    Google Scholar
  • 100 Lord C, Paul R. Language and communication in autism. In: Cohen DJ, Volkmar FR Handbook of Autism and Pervasive Developmental Disorders. 2nd ed. New York, NY; Wiley 1997: 195-225
    Google Scholar
  • 101 Carpenter M, Tomasello M. Joint attention, cultural learning, and language acquisition. In: Wetherby AM, Prizant BM Autism Spectrum Disorders: A Transactional, Developmental Perspective. Baltimore, MD; Brookes 2000: 31-54
    Google Scholar
  • 102 Prizant B, Schuler A, Wetherby A M, Rydell P J. Enhancing language and communication: language approaches. In: Cohen DJ, Volkmar FR Handbook of Autism and Pervasive Developmental Disorders. 2nd ed. New York, NY; Wiley 1997: 572-605
    Google Scholar
  • 103 Tsatsanis K. Heterogeneity in learning style in Asperger syndrome and high functioning autism.  Topics Lang Disord. 2004;  24 260-270
    PubMedGoogle Scholar
  • 104 Hoshino Y, Kaneko M, Yashima Y, Jumashiro H, Volkmar F R, Cohen D J. Clinical features of autistic children with setback course in their infancy.  Jpn J Psychiatry Neurol. 1987;  41 237-245
    PubMedGoogle Scholar
  • 105 Kientz M A, Dunn W. A comparison of the performance of children with and without autism on the Sensory Profile.  Am J Occup Ther. 1997;  51 530-537
    PubMedGoogle Scholar
  • 106 Anzalone M, Williamson G. Sensory processing and motor performance in autism spectrum disorders. In: Wetherby AM, Prizant BM Autism Spectrum Disorders: A Transactional Developmental Perspective. Baltimore, MD; Paul Brookes 2000: 143-166
    Google Scholar
  • 107 Baranek G. Efficacy of sensory and motor interventions for children with autism.  J Autism Dev Disord. 2002;  5 397-422
    PubMedGoogle Scholar
  • 108 Dawson G, Meltzoff A N, Osterling J, Rinaldi J, Brown E. Children with autism fail to orient to naturally occurring social stimuli.  J Autism Dev Disord. 1998;  28 479-485
    CrossrefPubMedGoogle Scholar
  • 109 Ahearn W H, Castine T, Nault K, Green G. An assessment of food acceptance in children with autism or pervasive developmental disorder-not otherwise specified.  J Autism Dev Disord. 2001;  31 505-511
    PubMedGoogle Scholar
  • 110 Schreck K, Williams K, Smith A. A comparison of eating behaviors between children with and without autism.  J Autism Dev Disord. 2004;  34 433-438
    PubMedGoogle Scholar
  • 111 Belsky J, Most R. From exploration to play: a cross-sectional study of infant free play behavior.  Developmental Psychology. 1981;  17 630-639
    CrossrefPubMedGoogle Scholar
  • 112 Casby M. Symbolic play: development and assessment considerations.  Infants Young Child. 1992;  4 43-48
    PubMedGoogle Scholar
  • 113 Bates E, Bretherton I, Snyder L, Shore C, Volterra V. Vocal and gestural symbols at 13 months.  Merrill Palmer Q. 1980;  2 407-423
    PubMedGoogle Scholar
  • 114 Thal D. Language and cognition in normal and late-talking toddlers.  Topics Lang Disord. 1991;  11 33-42
    PubMedGoogle Scholar
  • 115 Kennedy M, Sheridan M, Radlinski S, Beeghly M. Play-language relationships in young children with developmental delays: implications for assessment.  J Speech Hear Res. 1991;  34 112-122
    PubMedGoogle Scholar
  • 116 Lyytinen P, Laakso M, Poikkeus A, Rita N. The development and predictive relations of play and language across the second year.  Scand J Psychol. 1999;  40 177-186
    CrossrefPubMedGoogle Scholar
  • 117 Lyytinen P, Poikkeus A, Laakso M, Eklund K, Lyytinen H. Language development and symbolic play in children with and without familial risk of dyslexia.  J Speech Lang Hear Res. 2001;  44 873-885
    CrossrefPubMedGoogle Scholar
  • 118 Yoder P, Warren S, Hull L. Predicting children's response to two prelinguistic communication interventions.  J Early Intervention. 1995;  19 74-84
    PubMedGoogle Scholar
  • 119 Jarrod C, Boucher J, Smith P. Executive function deficits and the pretend play of children with autism: a research note.  J Child Psychol Psychiatry. 1994;  35 1473-1482
    PubMedGoogle Scholar
  • 120 Ferrara L, Hill S. The responsiveness of autistic children to the predictability of social and nonsocial toys.  J Autism Dev Disord. 1980;  10 51-57
    PubMedGoogle Scholar
  • 121 Riguet C, Taylor N, Benaroya S, Klein L. Symbolic play in autistic, Down's, and normal children of equivalent mental age.  J Autism Dev Disord. 1981;  11 439-488
    PubMedGoogle Scholar
  • 122 Charman T, Baron-Cohen S. Brief report: prompted pretend play in autism.  J Autism Dev Disord. 1997;  27 325-332
    PubMedGoogle Scholar
  • 123 Stone W, Lemanek K, Fishel P, Fernandez M, Altemeier W. Play and imitation skills in the diagnosis of autism in young children.  Pediatrics. 1990;  86 267-272
    PubMedGoogle Scholar
  • 124 Libby S, Powell S, Messer D, Jordan R. Spontaneous play in children with autism: a reappraisal.  J Autism Dev Disord. 1998;  28 487-497
    PubMedGoogle Scholar
  • 125 25th Annual Report to Congress on the Implementation of the Individuals with Disabilities Education Act. Office of Special Education and Rehabilitative Services. Washington, DC; US Department of Education 2003
    Google Scholar
  • 126 Early Intervention in North Carolina .Data from the Infant Toddler Program. Available at: http://www.ncei.org/ei/pdf/EIProfile2002.pdf Accessed June 1, 2006
    Google Scholar
  • 127 American Academy of Pediatrics . Developmental surveillance and screening of infants and young children.  Pediatrics. 2001;  108 192-196
    CrossrefPubMedGoogle Scholar

Elizabeth R CraisPh.D. 

Division of Speech and Hearing Sciences, CB7190

University of North Carolina at Chapel Hill, Chapel Hill, NC 27599

eMail: bcrais@med.unc.edu