Neuropediatrics 2006; 37 - THP67
DOI: 10.1055/s-2006-945890

EVALUATION OF IRON DEFICIENCY AND ADHD INTER RELATION SHIP IN PEDIATRIC NEUROLOGY OUT PATIENT

B Jalili 1, Z Oloomi 1, H Salarineghad 1, Z Taj 1, K Douste 1
  • 1Tehran, Iran

Objectives: ADHD is one of the most common child psychiatric problem and the role of elements especially Iron has been investigated in some studies. The etiology is unknown but the good effect of Iron the treatment of these patients has been found more and more.

Methods: One case control study retrospectively has been done. In 82 ADHA patients referred to shahid Esmaili psychiatric out patient and 82 patient referred to Emam Khomeini general pediatric out patient during 1380. They were adjusted by (age/sex) the age of patients 33(7–12 yr.) and 49 (10–12 yr.) from each group. There were 67 male each group the ADHD is diagnosed by child psychiatric as DSM-IV criteria without chronic disorders that can cause anemia and control group without ADHD and neurologic symptoms. We gathered data by observation, parents and patient interview and CBC, Ferritin, Fe, TIBC estimation we used statistical interpretation by t test, X2, and p-value <0/05 was significant Criteria of iron deficiency.

Results: There was iron deficiency in 34.1% of case and 22% of control (P<0/027) early onset iron deficiency 22% of case, 14/6% control (P=0.12) non significant. Late onset iron deficiency in 17.1% of case and 11% of control nonsignificant (P=0.16). Mean value of Hemoglobin level was (P=0.083) but MCH (P=0.31) and MCV (P=0.17) that was not significant. But mean value of serum iron (P=0.058), serum ferritin P=0.0009 as well as serum transferring P=0.033 and TIBC P- 0.0011 were significant.

Conclusion: In this study we have seen a significant difference between iron and ferritin deficiency and transferrin increasing but there was no significance for Hemoglobin, MCV and MCH between case and control. There are more and more evidence about effectiveness of iron substitution in alertness, concentration, attention, learning, psychomotor development in children. It seems that with doing more investigation for this as well as ADHD, we can do effective problem solving for children with ADHD.