Neuropediatrics 2006; 37 - CS2_1_1
DOI: 10.1055/s-2006-945536

MILD CLOSED HEAD INJURY

D MacGregor 1, S Menascu 1
  • 1Hospital for Sick Children, Toronto, ON, Canada

Objective: To review the literature on mild closed head injury with a focus on definitions and pathophysiological mechanisms.

Methods: A systematic review of the medical and psychological literature was completed and the results were analysed.

Results: Mild closed head injury in children should be assessed from a functional perspective. An agreed upon definition is an acute blow to the head or from acceleration/deceleration injury that correlates with a Glasgow Coma Scale of 13–15 and associated with temporary loss of consciousness, vomiting, lethargy and headache (including seizures occurring immediately after the impact).

Pathophysiological markers of head injury include S-100B (an acidic calcium-binding protein) and neuron specific enolase (NSE) which correlate relatively well with severe brain injury. There is a recognized association with the apolipoprotein a (APO a) 4 allele genotype.

A new simple binary classification of concussion has eliminated the need for injury grading scales. “Simple” concussion gradually resolves over a 7–10 day period. “Complex” concussion is characterized by persistent symptoms, prolonged loss of consciousness (<1 minute), convulsive or motor phenomenon or a history of multiple concussions (over time).

Conclusion: Mild traumatic brain injury is a common paediatric problem. The potential for long-term disability needs recognition.

Keywords: Closed head injury