Background and study aim: Endoscopic submucosal dissection (ESD) is a new and radical treatment for superficial
gastrointestinal neoplasms that provides high rates of en bloc resection compared
with treatment by conventional mucosal resection. However, ESD is a complex procedure
that is associated with long operating times and a higher complication rate. This
feasibility study assessed the use of a novel double-channel therapeutic endoscope
for performing en-bloc ESD in order to assess whether the procedure time could be
shortened.
Patients and methods: The therapeutic endoscope we used (the “R-scope”) is equipped with a multibending
system and has two movable instrument channels: one moves a grasping forceps vertically
for lesion countertraction; the other swings a cutting knife horizontally for dissection.
Twenty consecutive patients (18 men, 2 women; mean age 63 years, range 54 - 80 years)
with superficial gastric neoplasms in the distal two-thirds of the stomach underwent
resection of their tumor by ESD using the R-scope. Forty size- and location-matched
gastric neoplasms resected by conventional ESD were reviewed retrospectively for the
purposes of comparison.
Results: The rates of curative en-bloc resection, complications, and local recurrence using
the two ESD methods were comparable. The mean ± SD operating time was significantly
shorter for ESD using the R-scope than for conventional ESD (57.9 ± 29.7 minutes vs.
92.8 ± 58.9 minutes, P = 0.016).
Conclusion: The R-scope appears to shorten the operating time of ESD with comparable efficacy
and complication rates.
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M. Kaise, M. D.
Department of Endoscopy
The Jikei University School of Medicine · 3-25-8 Nishi Shinbashi · Minato-ku · Tokyo
103-8461 · Japan
Fax: +81-3-5438-8380
Email: kaise@jikei.ac.jp