Klinische Bedeutung des gastroösophagealen Refluxes beim Asthma bronchiale

Zusammenfassung

Im klinischen Alltag koinzidieren asthmatische Beschwerden und gastroösophagealer Reflux (GÖR) häufig. Bei der Behandlung einer gastroösophagealen Refluxkrankheit muss ein parallel bestehendes Asthma dann nicht mitberücksichtigt werden, wenn das Asthma gut kontrolliert ist. Im Falle eines symptomatischen Asthmas, das auch auf eine Therapieintensivierung nicht, oder nur unzureichend anspricht, besteht jedoch die Möglichkeit, dass der GÖR und die Therapierefraktärität des Asthmas in einem kausalen Zusammenhang stehen. Ein Algorithmus soll in diesem Fall das klinische Vorgehen leiten.

Abstract

In clinical practice, gastrooesophageal reflux (GER) and bronchial asthma often coincide. In the case of sufficient asthma control, the asthma does not need to be taken into account when treatment of GER is being evaluated. In patients with symptomatic asthma despite adequate antiasthmatic treatment, a possible causal relationship between GER and the poor responsiveness to asthma therapy has to be considered. An algorithm to guide the diagnostic and therapeutic steps in such cases is presented.

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