ABSTRACT
Locally advanced and locally recurrent colon cancers pose a surgical challenge with
tumors extending into surrounding structures and organs. Anticipation of the need
for an extended surgical resection, often with multivisceral en bloc organ removal,
is critical for surgical planning. For both primary and recurrent tumors, postsurgical
long-term survival is achievable but only after complete resection. The role of neoadjuvant
and adjuvant therapy continues to be redefined in this era of biologic chemotherapeutics,
and multimodality therapy holds promise in aiding resection and improving postsalvage
survival.
KEYWORDS
Locally advanced - recurrent - colon cancer - salvage - locoregional - surgery
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Martin R WeiserM.D.
Division of Colorectal Surgery, Memorial Sloan-Kettering Cancer Center
1275 York Ave., Rm. C-1075
New York, NY 10021
Email: weiser1@mskcc.org
