BAL beim Pferd - klinische Aspekte

Einleitung

Die broncho-alveoläre Lavage (BAL) beim Pferd wird bislang hauptsächlich als Diagnostikum bei chronischen Lungenerkrankungen von Hochleistungspferden (d. h. in Rennställen) oder bei der Erforschung der equinen COPD eingesetzt. Ziel der hier vorgestellten Untersuchung war es, die BAL auf ihre routinemäßige Durchführbarkeit an klinisch relevanten Pferdepatienten zu überprüfen.

Literatur

• 1 Robinson N E. International workshop on equine chronic airway disease, Michigan State University 16 - 18 June 2000.  Equine Vet J. 2001;  33 5-19
• 2 Venner M. Diagnostik von Gastropathien (Klinik, Endoskopie, Labor).  Vortragsband Bpt-Kongress, 4 - 7 November 2004 in Nürnberg.. 2004;  79-82
• 3 Sweeney C R, Weiher J, Baez J L. et al . Bronchoscopy of the horse.  Am J Vet Res. 1992;  53 1953-1956
• 4 Crane S A, Ziemer E L, Sweeney C R. Cytologic and bacteriologic evaluation of tracheobronchial aspirates from clinically normal foals.  Am J Vet Res. 1989;  50 2042-2048
• 5 Viel L, Hewson J. Bronchoalveolar Lavage. In: Robinson NE (ed): Current Therapy in Equine Medicine 5. Saunders 2003: 407-411
• 6 Schusser G F, Wiegand M, Ruhland A. Technik und Differenzialzellbild der bronchoalveolären Lavage bei Pferden mit COPD.  Prakt Tierarzt. 1999;  80 601-604
• 7 Fogarty U. Evaluation of a bronchoalveolar lavage technique.  Equine Vet J. 1990;  22 174-176
• 8 Lapointe J M, Vrins A, Lavoie J P. Effects of centrifugation and specimen preparation technique on bronchoalveolar lavage analysis in horses.  Equine Vet J. 1994;  26 227-229
• 9 Moore B R, Cox J H. Diagnostic use of bronchoalveolar lavage in horses.  Equine Practice. 1996;  18 7-15
• 10 McGorum B C, Dixon P M. The analysis and interpretation of equine bronchoalveolar lavage fluid (BALF) cytology.  Equine Vet J. 1994;  6 203-209
• 11 Mair T S, Stokes C R, Bourne F J. Cellular content of secretions obtained by lavage from different levels of the equine respiratory tract.  Equine Vet J. 1987;  19 458-462
• 12 Burns D M, Shure D, Francoz R. et al . The physiologic consequences of saline lobar lavage in healthy human adults.  Am Rev Respir Dis. 1983;  127 695-701
• 13 Crystal R G, Reynolds H Y, Kalica A R. Bronchoalveolar lavage: report of an international conference.  Chest. 1986;  90 122-131
• 14 Sweeney C R, Rossier Y, Ziemer E L. et al . Effect of prior lavage on bronchoalveolar lavage fluid cell population of lavaged and unlavaged lung segments in horses.  Am J Vet Res. 1994;  55 1501-1504
• 15 McKane S A, Canfield P J, Rose R J. Equine bronchoalveolar lavage cytology: survey of thoroughbred racehorses in training.  Aust Vet J. 1993;  70 401-404
• 16 Freeman K P, Roszel J F, McClure J M. et al . A review of cytological specimens from horses with and without clinical signs of respiratory disease.  Equine Vet J. 1993;  25 523-526
• 17 Clark C K, Lester G D, Vetro T. et al . Bronchoalveolar lavage in horses: effect of exercise and repeated sampling on cytology.  Aust Vet J. 1995;  72 249-252
• 18 Couetil L L, DeNicola D B. Blood gas, plasma lactate and bronchoalveolar lavage cytology analyses in racehorses with respiratory disease.  Equine Vet J Suppl. 1999;  30 77-82
• 19 Newton J R, Wood J L. Evidence of an association between inflammatory airway disease and EIPH in young Thoroughbreds during training.  Equine Vet J Suppl. 2002;  34 417-424
• 20 Colahan P T, Bailey J E, Chou C C. et al . Effect of flunixin meglumine on selected physiologic and performance parameters of athletically conditioned thoroughbred horses subjected to an incremental exercise stress test.  Vet Ther. 2002;  3 37-48
• 21 Dixon P M, Railton D I, McGorum B C. Equine pulmonary disease: a case control study of 300 referred cases. Part 1: Examination techniques, diagnostic criteria and diagnoses.  Equine Vet J. 1995;  27 416-421
• 22 Robinson N E, Berney C, Eberhart S. et al . Coughing, mucus accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction.  Am J Vet Res. 2003;  64 550-557
• 23 Giguère S, Viel L, Lee E. et al . Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate.  Vet Immunol Immunopathol. 2002;  85 147-158
• 24 Sandersen C, Bureau F, Turlej R. et al . p65 Homodimer activity in distal airway cells determines lung dysfunction in equine heaves.  Vet Immunol Immunopathol. 2001;  80 315-326
• 25 Gerber V, King M, Schneider D A. et al . Tracheobronchial mucus viscoelasticity during environmental challenge in horses with recurrent airway obstruction.  Equine Vet J. 2000;  32 411-417
• 26 Benamou A E, Art T, Marlin D J. et al . Effect of exercise on concentrations of immunoreactive endothelin in bronchoalveolar lavage fluid of normal horses and horses with chronic obstructive pulmonary disease.  Equine Vet J Suppl. 1999;  30 92-95