Exp Clin Endocrinol Diabetes 2005; 113(8): 471-474
DOI: 10.1055/s-2005-865752

J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Endoscopic Ultrasound Imaging of Insulinomas: Limitations and Clinical Relevance

P. H. Kann1 , M. Rothmund2 , A. Zielke2
  • 1Division of Endocrinology & Diabetology, Philipp's University Hospital, Marburg, Germany
  • 2Department of Surgery, Philipp's University Hospital, Marburg, Germany
Further Information

Publication History

Received: March 16, 2005 First decision: April 18, 2005

Accepted: May 23, 2005

Publication Date:
08 September 2005 (online)


Compared to other imaging methods, endoscopic ultrasound is the best procedure to localize insulinomas preoperatively. Positive finding furthermore confirms endocrinological diagnosis, especially considering the differential diagnosis of hypoglycaemia factitia by oral antidiabetics. However, it always has to be considered that endoscopic ultrasound imaging may reveal false positive and false negative results, and quality of the findings obtained by endoscopic ultrasound imaging depends to a large extent on the examiner's experience. An important issue of endoscopic ultrasound imaging in insulinomas nowadays is planning surgical strategy. As illustrated by three cases, endoscopic ultrasound imaging enables to identify patients that qualify for laparoscopic, minimal invasive surgery.


M.D. Peter Herbert Kann Professor of Endocrinology, Head

Division of Endocrinology & Diabetology
Philipp's University Hospital

Baldinger Straße

35033 Marburg


Email: [email protected]