Planta Med 2005; 71(4): 370-372
DOI: 10.1055/s-2005-864107
© Georg Thieme Verlag KG Stuttgart · New York

Cytotoxic Chromenes from Myriactis humilis

Jih-Jung Chen1 , Chang-Yih Duh2 , Ih-Sheng Chen3
  • 1Department of Pharmacy, Tajen Institute of Technology, Pingtung, Taiwan, Republic of China
  • 2Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China
  • 3School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
Further Information

Publication History

Received: July 12, 2004

Accepted: December 12, 2004

Publication Date:
27 April 2005 (online)


Two new chromenes, myriachromene and 2,2-dimethyl-6,7-methylenedioxy-2H-chromene, together with ten known compounds including α-tocopherylquinone, α-tocopherol acetate, diphenyl sulfone, β-carotene, chondrillasterol, β-sitosterol, β-sitostenone, vanillin, and vanillic acid were isolated from the whole plant of Myriactis humilis. The structures of these new compounds were determined through spectral analyses. Among the isolates, four compounds exhibited cytotoxicity (ED50 values < 4 μg/mL) against P-388 or HT-29 cell lines in vitro.


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Dr. J. J. Chen

Department of Pharmacy

Tajen Institute of Technology


Taiwan 907

Republic of China

Fax: +886-8-762-5308