The results of liver surgery for metastasis of CRC over the age of 70

The older generation (>70 y.) is neglected or underrepresented in the literature regarding the liver surgery, oncological treatment, and trials. The purpose of this study is to clarify whether the elder generation has higher complication rate, mortality and shorter survival compared with the group of patients under 70.

Material and method: The registry of liver metastasis of CRC origin covers 10 year period in our Department. Since Jan 1. 1995, altogether 382 cases were registered. The number of patients older than 70 years was 36. Patient's selection contained the Karnofsky index, the general aspects of anesthesia, and the estimation of reserve liver capacity. Two groups of patients were created. Group I was consisted of patients over 70 y., since patients of Group II were under 70.

Results: Major complications were listed such as pneumonia, bleeding, bile collection or abscess development, and bile fistula. The complication rate in the group of the elderly has been: 21% vs. 17% (ns.) Mortality rate is found 3,1% vs. 3,5% (ns.) No significant difference is found between the 5 year survival rate (40% vs. 39%, ns.).

Discussion: The analysis showed no significant difference in morbidity, mortality and survival in patients resected for liver metastasis of CRC above the age of 70. The careful judgment for anesthesia, liver capacity and risk factors met with the patient's selection, although the general selection criteria were the same in younger population. In conclusion, the older generation should be evaluated for oncological surgery and to oncological treatment, because age is not contraindication anymore.