Abstract
To investigate the impact of acute salbutamol intake on performance and selected hormonal
and metabolic variables during supramaximal exercise, 13 recreational male athletes
performed two 30-second Wingate tests after either placebo (PLA, lactose) or salbutamol
(SAL, 4 mg) oral administration, according to a double-blind and randomized protocol.
Blood samples collected at rest, end of the Wingate test, recovery (5, 10, 15 min)
were tested for growth hormone (GH), insulin (INS), blood glucose (GLU), and lactate
determination. We found the peak and mean power performed significantly increased
after SAL vs. PLA (PPSAL: 896 ± 46; PPPLA: 819 ± 57 W; MPSAL: 585 ± 27; MPPLA: 534
± 35 W, p < 0.05), whereas no change was observed in the fatigue index. Blood glucose
and INS were significantly increased by SAL at rest, at the end of the Wingate test,
and during the 5 first minutes of recovery (p < 0.05). Plasma GH was significantly
decreased by SAL (p < 0.05) during the recovery whereas end-exercise and recovery
blood lactate tended but were not significantly increased after SAL vs. PLA. From
these data, acute salbutamol intake at therapeutical dosage did appear to improve
peak power and mean power during a supramaximal exercise, but the mechanisms involved
need further investigation.
Key words
β2-agonist - acute intake - performance - supramaximal exercise - hormone - lactate
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Katia Collomp
Laboratoire de la Performance Motrice, Faculté du Sport et de l'Education Physique
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