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Semin Reprod Med 2003; 21(4): 339-352
DOI: 10.1055/s-2004-815590
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Disorders of Pubertal Development: Precocious Puberty

Nirupama Kakarla, Karen D. Bradshaw
  • Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas
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Publication History

Publication Date:
14 January 2004 (online)

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ABSTRACT

Puberty is a complex developmental process culminating in sexual maturity. This transitional period begins in late childhood and is characterized by maturation of the hypothalamic-pituitary-gonadal axis, the appearance of secondary sexual characteristics, acceleration of growth, and, ultimately, the capacity for fertility. Significant endocrinologic changes accompany these developmental events. Disorders of pubertal development may occur at any of the steps of the maturational process leading to either precocious or delayed puberty. A thorough understanding of the normal pubertal process is important to the accurate diagnosis and treatment of pubertal disorders.

KEYWORDS

Puberty - precocious - gonadotropin-dependent - gonadotropin-independent

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